Just re-reading the question ...
I would like to reduce the payments on account due for 2010-11
The POAs were due to be paid on 31-01-2011 and 31-07-2011. The tax return was due by 31-10-2011 (paper) or 31-01-2012 (internet). I don't think that you can reduce them now.
Once your 2010-11 return is processed, then the system will set the 2011-12 POAs as 50% each of the total liability from 2010-11. It is the 2011-12 POAs which need to be adjusted because of your ceased self employment.
If you have no significant expenses for 2011-12, then simply calculate POAs as follows: £2,500 @ 40% = £1,000 = 2 POAs at £500 each.